ABSTRACT
This article comes from abundant experiences of TCM therapy of children cough variant asthma, on basis of theory of "pathogen usually intruding into collateral in protracted disease" and Treating "hidden stagnation" theory from Peng Bo, and according to physiology characteristic of children and conclusion of pathology experiment, inquires into mechanism and prescription of treating the disease from hidden wind and stagnation. This method demonstrates essence of TCM pathology of cough variant asthma, embodies the marrow of "curing the illness from essence", expects to obtain break-through about both theory of Chinese Medicine and practice .
ABSTRACT
AIM: To explore the influence of herbs (9602 prescription) on brain energy metabolism in cerebral ischemia reperfusion mice.METHODS: Ischemia reperfusion in cerebral injury model was duplicated in mice. Using nuclear magnetic resonance (NMR) and high performance liquid chromatography (HPLC), the brain metabolism were measured. The influence of 9602 prescription on cerebral energy metabolism in ischemia reperfusion mice model was dynamicly observed. RESULTS: Phase Ⅰ: The spectrum of NMR showed that after 10 min of ischemia, the PCr peak dropped significantly, while the Pi peak rose significantly in both the control and the “9602” group. There was no remarkable difference between the two groups. After reperfusion the PCr peak in the control group continued dropping slowly and remained at a low level (55.50?14.94) after 10 min of reperfusion, while after reperfusion the fallen PCr peak in the “9602” group started rising till 76.72?13.37 (P0.05). Phase Ⅱ: The HPLC showed that the cerebral energy charge values of the control group (0.1104?0.0343) were significantly lower than those of the “9602” group (0.2884?0.0552) and the sham-operation group (0.1846?0.0455) (P